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Chunk #33 — Fig 2

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Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors.
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Effect of age on posterior distribution of Bayesian Odds Ratios of 5-HTTLPR on BSI-ANX.BSI: Brief Symptom Inventory; BSI-ANX: BSI anxiety score. Curves display outlines of posterior distributions of Bayesian Odds Ratios of 5-HTTLPR ss versus ll genotype with respect to BSI-ANX (severe vs. low). An odds ratio greater than 1 represents risk for BSI-ANX. Odds ratios are given in different age groups (all population; equal and below 30; and above 30). All curves are highly peaked that indicates that all the possible models entail highly similar odds ratios, and the Bayesian Odds Ratio values show a moderate 5-HTTLPR ss genotype effect in the total population, strong effect in the younger subjects and negligible effects in the elder subpopulation.