Seven of the 10 variants associated with fast beta EEG were also associated with AD in a subset of the discovery GWAS sample (Table 4); the minor allele was associated with reduced AD risk, indicating a protective effect. Given the high LD observed among these 10 SNPs, these P-values were adjusted for the number of tests (1.2) as estimated using the Pnorm procedure.45 Four of these variants survived multiple test correction: rs7428372 (β: − 0.164, P-value<0.037), rs11705903 (β: − 0.161, P-value<0.039), rs6806557 (β: − 0.161, P-value<0.041), and rs13093097 (β: − 0.172, P-value<0.027).
