In the Braineac database, rs11720469 is associated with the mRNA expression of BCHE, PDCD10, SERPINI1, WDR49 and ZBBX. Only one of these findings survived a Bonferroni multiple test correction: rs11720469 is an eQTL for BCHE expression in thalamus tissue (P = 4.20 × 10−4); the minor allele is associated with decreased mRNA expression (Table 3). In the GTEx database, rs11720469 is associated with the expression of BCHE in brain tissue: cortex (P<0.007) and caudate (P<0.005). HaploReg V4.154,55 indicated that rs11720469 alters regulatory motifs in some cell types in the ROADMAP Epigenomics data.56
