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Chunk #3 — Materials and Methods — Subjects

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Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus.
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Celiac patients, recruited at City of Hope and Mayo Clinic, were reviewed for concomitant diagnoses of dermatitis herpetiformis and microscopic colitis. The presence of dermatitis herpetiformis was based on either a confirmatory skin biopsy or clinical documentation of the skin biopsy diagnosis in the medical record that included demonstration of IgA deposits at the dermo-epidermal junction. The presence of microscopic colitis was based on either clinical documentation of the diagnosis in the medical record or confirmatory colonic biopsies showing either lymphocytic or collagenous colitis.