A by‐product of the high‐risk, familial structure of the COGA sample, with its elevated rates of AUD, is an increased number of participants who enter remission from AUD compared with the general population. Thus, the search for the genetics that underpin AUDs has produced a sample that is well‐positioned to examine genetic, environmental, and familial influences on remission, an advancement over self‐selected samples. 108 , 109 The genetic and brain function data available from COGA participants can contribute to the evolving field of recovery science, which to date has been based largely on self‐selected samples of individuals who consider themselves to be in recovery but which lacks objective measures of recovery and biomarkers. 110
