Our results also extend findings of previous studies implicating other genes in determining variation in alcohol consumption and related phenotypes (e.g. MaxDrinks), especially in European-ancestry populations, including AUTS2, SGOL1, and SERPINC1. Schumann et al. previously reported a genome-wide association with alcohol consumption for AUTS2 rs6943555 in a meta-analysis combining 26,316 European-ancestry individuals.27 Two other studies conducted in European-ancestry populations identified potential novel loci associated with MaxDrinks, including SGOL1 rs11128951,28 and SERPINC1 rs1799876.26 We obtained modestly consistent results for these loci with alcohol consumption during the past year in our independent non-Hispanic white sample.
