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Chunk #38 — Results — Males and females demonstrate similar levels of genetic correlation between OCD and other complex traits

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Sex differences in the genetic architecture of obsessive-compulsive disorder.
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A genetic correlation analysis using sex-combined summary statistics for OCD and other traits, revealed several significant cross-trait correlations, indicating that a larger sample size results in more precise estimates of the genetic correlation. We observed novel significant genetic correlations between the sex-combined OCD sample and the sex-combined summary statistics from age at first birth (rg=0.37, se=0.07, 4.83e-07), number of children ever born (rg=−0.35, se=0.09, p=6.66e-05), and replicated previously published results (Brainstorm Consortium et al. 2018; Davis et al. 2013; Yu et al. 2015).