Like other GWAS of similar size, our ASD-only results are not definitive with the observed associations falling short of accepted statistical significance thresholds. However, we view these data as an important step in the ongoing endeavour to identify the loci which underpin the common variant signal in ASD and we anticipate that some of these loci of ‘borderline’ significance, especially those with additional corroborating evidence such as EXT1, ASTN2, MACROD2, and HDAC4, to eventually garner sufficient evidence to become established robust ASD risk loci.
