In the current study, we have employed a significance threshold of 5 × 10-8, as this threshold has been commonly used in previous GWA studies. As there were no SNPs that exceeded this threshold, we report the most significant SNP for each sample, as well as regions where there are 5 SNPs within 100 kb of each other all with p < 1 × 10-4. In addition, we list all SNPs reported with a p < 10-4 (Tables S3-S5). The strongest test of association lies in follow-up replication studies, however, and with the data we have available to us, we have attempted to examine the consistency of our results with previous GWA studies of BD and with our own newly genotyped replication samples (Table 3).
