Based on these results, the minimum GABAB1 gene length is estimated to be 72,333bp (chr6:29,653,437-29,725,769) of hg18 (Figure 4). This GABAB1 gene length is 41,375bp longer than the known GABAB1 length of 30,958bp (chr6:29,677,984-29,708,941). The minimum GABAB1 gene length from UCSC genome browser databases (i.e., human mRNAs from GeneBank and human ESTs that have been spliced) is 100,266bp (chr6:29,631,387-29,731,652) (Figure S1 in Supplement 1). These findings provide strong evidence that the GABAB1 gene is larger than previously reported.
