Ethanol sedation sensitivity and internal ethanol concentrations in w null and w wild-type fliesST50 values in response to vapor from 50% ethanol were indistinguishable in w null (w1118) and w wild-type (w+) females (panel A, unpaired t-test, n.s., n=6 for w1118, n=21 for w+) or males (panel B, (unpaired t-test, n.s., n=10 per genotype). C and D. Internal ethanol concentrations in response to vapor from 50% ethanol were not distinguishable in w1118 and w+ females (C) and males (D), but were affected by duration of ethanol exposure (individual two-way ANOVAs; effect of w genotype, n.s.; effect of ethanol exposure time, p<0.0001; n=5 per genotype, sex and exposure time).