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Chunk #21 — RESULTS — Effects of SDPS on alcohol taking and alcohol seeking — Retraining on FR1

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Stress vulnerability promotes an alcohol-prone phenotype in a preclinical model of sustained depression.
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effect in responding after PR was observed in the SDPS‐prone group, which displayed higher number of active responses when compared with both control (P = 0.001) and SDPS‐resilient (P = 0.018) groups at the first reFR1 session. Together, retraining in FR1 further indicated a stable, long‐term (~5 months after defeat) SDPS‐triggered increase in alcohol taking that was more prominent in the SDPS‐prone rats.