In this study, we investigated the relationship between frequency bands and functions related to the classical auditory oddball task in patients with schizophrenia and control subjects. Several investigations showed changes in the time- and frequency-dependent spatiotemporal distribution of cerebral oscillation [45-50]. We conducted time-frequency studies using a 160-channel whole-head MEG system and EEG, and investigated whether schizophrenia patients exhibit changes in ERD and ERS in the theta (4–8 Hz), lower alpha (8–10 Hz), upper alpha (10–13 Hz), and beta (13–30 Hz) bands while performing the conventional auditory oddball task. As far as we know, there are few studies using MEG of ERD and ERS in male patients with schizophrenia during the oddball task. In this study we applied a newly developed adaptive spatial filtering algorithm optimized for robust source time-frequency reconstruction from MEG and EEG data [49].
