Importantly, in all of these eye diseases, the fate of implanted cells can be more readily visualized, and functional outcomes more clearly assessed, than with intracerebral grafts of any type. Indeed, the safety of cell therapeutics in eye disease can be more confidently ascertained, in that if tumorigenesis or other serious adverse events are realized, then enucleation of the affected eye – which would have lacked significant vision in order to necessitate treatment -would be a viable option.
