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Chunk #28 — HOPE: CNS DISEASE TARGETS FOR CELL REPLACEMENT THERAPY — Disorders of the eye: Retinal diseases

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Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking.
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intrinsic retinal disorders and optic neuropathies may prove appropriate targets for phenotype-specific cell replacement. In particular, both rod and cone photoreceptors, lost in disorders as varied as macular degeneration, retinitis pigmentosa and glaucoma, among other etiologies, appear potentially replaceable by stem cell-derived photoreceptors, and may be promising adjuncts to RPE transplants as well (Jayakody et al., 2015; Warre-Cornish et al., 2014; West et al., 2012).