In children and adolescents, the common heterogeneity SD for efficacy (teachers' and clinicians' ratings) and tolerability was 0·355, 0·188, and 0·268, respectively. In adults, the common heterogeneity SD for efficacy rated by clinicians and tolerability was 0·178 and 0·282, respectively. The test of global inconsistency did not show any significant difference for the primary outcomes. Additional details are reported in the appendix (p 474).