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Chunk #33 — Discussion

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Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results.
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Finally, more generally, there are now numerous guidelines for candidate gene studies (Chanock et al., 2007, Pearson and Manolio, 2008). If these guidelines are followed at all stages of the scientific process (from study design through review), the published literature will better reflect the genetic architecture of schizophrenia.