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Chunk #18 — Results — EEG functional connectivity patterns and associations with childhood trauma

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Childhood trauma is associated with developmental trajectories of EEG coherence, alcohol-related outcomes, and PTSD symptoms.
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Results of LGCMs estimating the unconditional mean intercept and linear slope of EEGc over time are displayed in Table 2. There was significant positive mean intercept and slope of all three frontal alpha EEGc pairs, indicating that overall, coherence tended to increase over time. The association of CPAT, CSAT, and CNAT with intercept and slope of frontal alpha EEGc, and the association between slope and intercept with AUD symptoms in male and female participants are displayed in Table 3. In the male-only model, we observed a significant association between CPAT and intercept (ß = −0.17, p = 0.010) and slope (ß = 0.11, p = 0.006) of LFC alpha EEGc (FZ-CZ--F3-C3). This suggests that males who reported CPAT had lower values at baseline, but a faster rate of change in EEGc over time. This association was not observed in male RFC or PFI alpha EEGc (FZ-CZ--F4-C4 and F8-F4--F7-F3, respectively). In contrast, in female participants, we observed a significant association between CSAT and intercept (ß = 0.13, p = 0.008) and slope (ß = −0.07, p = 0.016) of LFC alpha