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Chunk #19 — Results — EEG functional connectivity patterns and associations with childhood trauma

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Childhood trauma is associated with developmental trajectories of EEG coherence, alcohol-related outcomes, and PTSD symptoms.
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RFC or PFI alpha EEGc (FZ-CZ--F4-C4 and F8-F4--F7-F3, respectively). In contrast, in female participants, we observed a significant association between CSAT and intercept (ß = 0.13, p = 0.008) and slope (ß = −0.07, p = 0.016) of LFC alpha EEGc (FZ-CZ--F3-C3), as well as the intercept (ß = 0.16, p = 0.002) and slope (ß = −0.07, p = 0.024) of PFI alpha EEGc (F8-F4--F7-F3). This indicates that female participants who reported CSAT had higher initial values of LFC and PFI alpha EEGc, and a decreased rate of change in LFC and PFI alpha EEGc over time. We observed no significant associations between CNAT and EEGc, and no associations between CSAT or CPAT on our measure of RFC alpha EEGc (FZ-CZ--F4-C4). Greater parental education was associated with decreased intercept (ß = −0.02, p = 0.003) of LFC alpha EEGc in males but had no association with intercept or slope in females. Table 2.Results of the unconditional linear growth model for repeated measures of three frontal alpha EEG coherence Pairs in adolescent male and female COGA participantsLeft frontal-central (LFC) EEG coherenceFZ-CZ--F3-C3Right frontal-central (RFC) EEG coherenceFZ-CZ--F4-C4Prefrontal interhemispheric (PFI) EEG coherenceF8-F4--F7-F3MalesFemalesMalesFemalesMalesFemalesBeta (s.e.)pBeta (s.e.)pBeta (s.e.)pBeta (s.e.)pBeta (s.e.)pBeta (s.e.)pUnconditional linear growth modelIntercept Mean0.41 (0.02)<0.0010.46