protein 3 (NLRP3) inflammasome signaling are other consequences of immune activation which feed for-ward to perpetuate inflammation (Montesinos et al., 2016a). Importantly, the production of anti-inflammatory factors, such as interleukin-10 (IL-10) and transforming growth factor beta (TGF-β), is critical to control and resolve immune/inflammatory responses (Crews et al., 2011).
