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Chunk #19 — MATERIALS AND METHODS — Statistical Methods

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Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD).
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We used the FACTOR procedure in SAS version 9.2 (SAS Institute Inc., Cary, NC) to determine the factor structure of ADsx, ASPDsx, ADHDsx, CDsx, DDsx, and NS scores. All phenotypes were entered into a principal component analysis using the default orthogonal rotation method. We then calculated factor scores for each individual with nonmissing data for all disinhibitory phenotypes and tested for association with these scores.