symptoms across these subgroups corresponded to heavy drinking frequency over follow-up (Figure 1B). Of note, the classifications of individuals in the AUD symptom trajectory subgroup were fairly stable, relative to the classifications of initial heavy drinkers in the 5-year analysis (11). Eighty-one percent of the participants remained in their respective low, intermediate, and high AUD SX subgroup, while 15% moved by one category to the next higher SX group, and 4% changed to the next lower group.
