The first blood oxygenation level-dependent (BOLD) signal was generated by a one-sample t-test specified to a contrast between seeing images of alcoholic beverages versus images of non-alcoholic beverages in the patient group. The second blood oxygenation level-dependent (BOLD) signal was generated by a conjunction analysis assessing a comparison of viewing images of alcoholic beverages to control images versus a comparison of viewing images of non-alcoholic beverages to control images across all patients. The one-sample t-test and conjunction analysis were both conducted at voxel level and a threshold for significant functional activation at p < 0.01 uncorrected for the one-sample t-test and p < 0.001 uncorrected for the conjunction analysis. The set of cluster size was larger than 60 voxels in the one-sample t-test and larger than 50 voxels in the conjunction analysis.
