Chunk #15 — Methods — The QTLD test

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The quantitative trait linkage disequilibrium test: a more powerful alternative to the quantitative transmission disequilibrium test for use in the absence of population stratification.

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1) Test for Stratification (Model 2 vs. Model 3) – The likelihood of a model in which the association parameters, βb and βw, are estimated is compared to the likelihood of a model in which they are constrained to be equal, as would be the case in the absence of population stratification.