mRNA expression data in the Dorso-lateral Pre-frontal cortex (DLFPC) region of the human brain was generated in 138 brains obtained from the New South Wales Brain Bank (NSWBB). We also had access to alcohol consumption (gm/day) data in a subset of 92 brains. Alcohol-dependence diagnoses and consumption data were collected by physician interviews, review of hospital medical records, questionnaires to next-of-kin, and from pathology, radiology, and neuropsychology reports.
