The Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) was used to interview all subjects. The SSAGA is a comprehensive diagnostic interview with documented reliability and validity (Bucholz et al., 1994; Bucholz et al., 1995; Hesselbrock et al., 1999) developed specifically for the COGA study and accommodates several diagnostic systems, including information that allowed classification of AUD by the recent Fifth Diagnostic and Statistical Manual (DSM5) of the American Psychiatric Association (2013).