techniques the authors demonstrated that in healthy subjects, the current maxima shifted rapidly from premotor cortex to right sensorimotor cortex and then left premotor and sensorimotor regions, whereas, in schizophrenic patients, cortical activation was more localized, shifting slowly between premotor and motor areas along the midline. Taken together, these results suggest that effective connectivity in schizophrenic patients is impaired, especially with regards to the capacity to produce and synchronize gamma activity. These results mesh well with the findings of Fitzgerald et al (2007) and Vercammen et al (2010a), which also suggested decreased functional connectivity.
