This study identified several other genes for DPW with multiple lines of evidence (eQTL, mQTL, differential expression; FDR < 20%; HEIDI P > 0.05; GWAS P < 5 × 10−5). For example, at locus 16p11.2, SULT1A1 and SULT1A2 were the strongest candidates with co-localization evidence emerging from mQTL and eQTLs from adult brain tissue (Supplementary Data 5; Supplementary Data 6). On chromosome 19, FUT2 was the strongest candidate; mRNA expression of FUT2 was also nominally associated with increased alcohol consumption (Beta = 0.09, P = 4.6 × 10−2) when comparing the DLPFC of individuals with AUD and control subjects (Supplementary Data 5).
