Samples were dissected at each of the brain banks and shipped to Icahn School of Medicine - Mt Sinai (ISMMS) for sample preparation, genotyping, and RNA-sequencing. Dissection protocols were as follows:MSSM: All samples for the study were dissected from the left hemisphere of fresh frozen coronal slabs cut at autopsy from the dorsolateral prefrontal cortex from Brodmann areas 9 or 46. Immediately after dissection, samples were cooled to −190 °C and dry homogenized to a fine powder using a L-N2 cooled mortar and pestle. Tissue was transferred on dry ice to ISMMS as a dry powder for DNA and RNA extraction.Penn: At autopsy, right or left hemisphere of each brain was blocked into coronal slabs, which were immediately frozen and stored at −80 °C. For this study, the Brodmann areas 9 or 46 were dissected from either the left or right hemisphere and pulverized in liquid nitrogen. The tissue was shipped in tubes appropriate for DNA or RNA extraction to ISMMS as homogenized tissue in trizol for RNA extraction and dry pulverized tissue for DNA extraction.Pitt: At autopsy, the right
