A final approach uses mixture regression models to take full advantage of the individual genotype posterior probabilities. This approach should be superior when there is uncertainty in the imputed genotypes, and information about the relationship between genotype and phenotype is not well summarized by a single average genotype. For example, this may occur when the posterior probabilities are high for the two homozygote genotypes, yet an average or allelic dosage would indicate that unmeasured genotype was a heterozygote.
