The second contrast tested whether the heritability estimate differed as a function of the assessment method. Specifically, several studies used population registries or hospital records to infer AUD while others relied on clinical interviews. There was no statistically significant difference between the assessment methods (χ2 = 0.31, df = 1, p = 0.58). Accordingly, there is no evidence of heterogeneity in the heritability estimate due to sex or assessment method. The likelihood ratio tests results are presented in Table 4.