In the first part of this study, we confirmed the association of rs1344706[T] with schizophrenia (P = 0.0029), using genotypes from 5164 schizophrenia cases and 20 709 controls. Although, in this study, only a modest number of bipolar disorder cases was available (N= 609), adding these cases to the analysis increased the evidence for association, in line with the original report. Thus, rs1344706[T] may confer risk of both schizophrenia and bipolar disorder, a finding consistent with epidemiological studies suggesting shared genetic risk factors for the two diseases.20,21