FASTSNP applies web wrapper agents (2,3) to resolve this problem. A web wrapper agent is a script that defines a user browsing session. When executed, the agent will visit the target website, fill in the query forms, extract the returned data and perform other web interactions to complete the user browsing session. Since FASTSNP uses the agent to access the external web servers at query time, the information used to prioritize SNPs is always the most up-to-date information available.