trajectories increased. Interestingly, the NCX expression trajectory for synapse development (Fig. 5c, d) did not display a drastic decline during late childhood or adolescence as previously reported for synapse density42. We also identified network modules and additional genes that are highly correlated with the categories (Supplementary Tables 13 and 14). For example, M20 and M2 were strongly correlated with neuron migration (r=0.894) and myelination (r=0.972), respectively.