In addition, our dataset allowed us to generate expression trajectories of genes commonly associated with ASD and schizophrenia. We investigated a number genes previously linked to these disorders (Supplementary Information 6.10) and observed distinct and dynamic expression patterns, especially among NCX areas, including examples for CNTNAP2, MET, NLGN4X, and NRGN shown in Supplementary Figure 25. To gain insight into potential biological functions of ASD and schizophrenia-associated genes in human neurodevelopment, we identified other genes with significantly correlated spatiotemporal expression profiles and performed GO enrichment analysis (Supplementary Tables 15 and 16). These findings reveal spatiotemporal differences associated in these expression trajectories and provide additional co-expressed genes that can be interrogated for their role in the respective processes or disorders.
