Chunk #10 — Results — Association of brain phenotypes with cell types from the mouse central and peripheral nervous system

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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.

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We leveraged gene expression data from 39 broad categories of cell types from the mouse central and peripheral nervous system 30 to systematically map brain-related traits to cell types (Figures 2A, S5). Our use of mouse data to inform human genetic findings was carefully considered (see Discussion).