Chunk #19 — Results — Short-term selective breeding (STSB) for ethanol consumption

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Detection of reciprocal quantitative trait loci for acute ethanol withdrawal and ethanol consumption in heterogeneous stock mice.

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The data in Fig. 5 illustrate acute ethanol withdrawal at S4 in the STSB lines for ethanol consumption. The CAUC (relative units) for the High and Low lines was 5.91±1.14 vs 12.1±1.27 (p<3 × 10−4). The CMAX was also significantly different—2.18±0.24 vs 3.28±0.20 (p<5 × 10−4). The difference in the baseline scores was not significant (p>0.4).