scatter plot and switch the fine-mapping tools via a drop-down box. The link on the hover tip can directly guide users to the causal block viewer of a particular study. As fine-mapping would have narrowed down the significant variants to a smaller set, users sometimes may get no results when searching for rsID. We have included an additional query function for users to browse variants with genome-wide significance by clicking ‘Only show P-value’ in a phenome-wide-like plot (Supplementary Figure S7). In addition, we listed the traits associated with potential pleiotropy of queried variant in this plot. On searching for a trait name, auto-completion should help users select the potential trait from the mapped MeSH terms. In the search result, users can see all causal blocks across the studies related to the searched trait in a heatmap plot (Figure 2B). Each column represents an independent causal block and each row depicts a separate GWAS. The grid color in the heatmap represents the number of potential causal variants in a corresponding causal block. On the hover tips, users can find the median GWAS P-value of the credible set, and on clicking the block genomic position, they can navigate to the corresponding block
