Locus 2 (rs578776) also shows evidence of association with lung cancer in single-SNP analysis (p = 9.74×10−10; OR = 0.82 (0.77–0.87)) (Figure 5). Locus 3 results in a p-value of 0.0004 (OR = 0.90 (0.86–0.96)) (Figure 6); as with categorical CPD, this meets our multiple-test-corrected threshold but is not genome-wide significant. Locus 4 shows no evidence for association with lung cancer; the forest plot is given in Figure S3.
