Nine out of the 11 previously reported variants suggestively associated with AN42 were found in our discovery meta-analysis, and six of these 9 SNPs had the same direction of effect as originally reported (P=0.508) (Table S9). Twelve out of 14 variants previously reported to be associated with eating disorder-related symptoms, behaviors, and personality traits59, 60 were found in our discovery meta-analysis and 7 had the same direction of effect (P=0.774) (Table S10), with one SNP (inside RUFY1) having P<0.05 (binomial P=0.459). We did not find evidence for signal enrichment in the 60 independent SNPs found in the Psychiatric Genomics Consortium data for ADHD, schizophrenia, bipolar disorder, or major depressive disorder63-66 (Table S11).
