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Chunk #13 — Methods and materials — Statistical analysis

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Subcortical volumes are reduced in short-term and long-term abstinent alcoholics but not those with a comorbid stimulant disorder.
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We examined the associations (separately for STAA DAO, STAA DASD, LTAA DAO, and LTAA DASD) between subcortical volumes and measures of alcohol, stimulant, and nicotine use (including days abstinent), and with mood and anxiety diagnoses using Spearman correlations. We also examined associations with subcortical volumes of CANTAB tests that showed impairments in STAA vs. NSAC (Affective Go/No-go, Delayed Matching to Sample, Motor Screening, and both Spatial Recognition Memory and Spatial Working Memory), and compared STAA DAO with STAA DASD on those CANTAB tests.