by Hypothesis 1 and several reports in the literature (e.g., Stinson et al., 2005; Teeson et al., 2010), the presence of either an AUD or a SUD was associated with an increased rate of the other diagnosis. This increase for SUDs among subjects with AUDs was in the range of individuals with alcohol abuse who developed a SUD as reported in an earlier study (Goldstein et al., 2012), although not as great an increase in SUDs evidenced in subjects with alcohol dependence in that investigation. The less robust increase in the present study compared to some prior reports may reflect the exclusion from the protocol of subjects with severe antisocial problems, the few subjects with a FH of SUDs, and the overall high functioning of these probands.
