The combined discovery meta-analysis, incorporating both sexes, did not identify genetic variants of genome-wide significance (N=16,400, lowest p= 6.1 x 10-7). The strongest associations were located on chromosome 20, followed by chromosomes 1, 19, 22 and 6 (see Manhattan plot, Figure S1A). SNPs yielding p values smaller than p= 1.0 x 10-6 were considered to be suggestive (Table S2a).