Participants were adult (18 years or older) patients (n=205), parents/guardians of pediatric patients (n=103), and family members acting as matched case controls (n=28) who were recruited to one of six ongoing genomic studies (pediatric brain cancer, pediatric brain controls, pediatric autism, adult/pediatric epilepsy, adult/pediatric liver cancer, and adult pancreatic cancer) at Baylor College of Medicine (BCM) in Houston, Texas between January 2008 and August 2009.