Participants eligible for the randomized consent study were English proficient and were enrolled with a waiver of consent obtained from the BCM Institutional Review Board (IRB). Participants considering enrollment in one of the genomic studies were randomized to one of three experimental consent types via a centralized, web-based randomization program using permuted blocks and stratified by genomic study. Genomic study PI’s who could not use the online randomization system were provided with sealed, pre-randomized envelopes each containing the assignment. Informed consent into the genomic study was obtained in a face-to-face setting by the genomic study PI, a research nurse, or a medical resident with one of the three experimental consent documents. The consent process varied slightly depending on the design of the underlying genomic study; however, the overall process did not differ by randomized consent type.
