The gPROSPER sample includes 2,032 youth participating in the larger PROSPER project who provided buccal cell samples for genotyping. Of the 2,032 youth who provided buccal cell samples, 537 did so during the Wave 5 in-home assessment, and the remaining 1,495 provided samples through the mail as part of a young-adult follow-up assessment. The gPROSPER study is adequately powered to detect associations – including main effects and interactions in multiple regression analysis – even with small effect sizes, with over 99% power to detect partial correlations of 0.1 or greater. DNA was collected via buccal cell samples from all gPROSPER youth. Youth were compensated $25 for their participation in the DNA collection. Of the 2,032 participants who provided DNA samples, 94% (1,920) were successfully genotyped for the GABRA2 rs279845 SNP [TaqMan assay # C___8263012_10 conducted on an OpenArray system (Life Technologies, Thermo Fisher)]. For the remaining 6% of participants, the GABRA2 rs279845 genotype could not be determined based on the DNA samples provided. The 1,920 youth successfully genotyped for GABRA2 rs279845 make up the analytic sample of the current study
