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Chunk #1 — Method

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PROSPER Intervention Effects on Adolescents' Alcohol Misuse Vary by GABRA2 Genotype and Age.
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Intervention was provided via the PROSPER delivery system, which supported the delivery of evidence-based preventive intervention through a school-community-university partnership (see Spoth, Greenberg, Bierman, & Redmond, 2004). The intervention consisted of two types of evidence-based programs (chosen from a short menu provided to community teams): (1) a voluntary family-focused intervention (delivered in the spring semester of 6th grade, 2003 and 2004 for Cohorts 1 and 2, respectively) and (2) a school-based intervention (delivered in 7th grade, 2004 and 2005 for Cohorts 1 and 2, respectively). The interventions targeted social norms, personal goal setting, decision-making, peer group affiliation, the parent-child relationship, and family-functioning. High levels of implementation quality were observed (Spoth, 2007; Spoth et al., 2007). See Figure 1 for the PROSPER CONSORT diagram (for design details, see Spoth et al., 2013).