ITIH5, SHANK2 and C15orf32 showed nominal association with HOD, modest association with AUD-FS, but without confirmatory association with AD diagnosis (see Table S9 in the Supplement), as did a number of non-genic SNPs. Overall, 22 of 64 SNPs nominally associated with HOD also showed association with AUD-FS at p<.005, compared with only 4 of 51 SNPs associated with 12-month weekly consumption that were also associated with AUD-FS (not shown).