locus 1 and locus 2, the significance at locus 2 is reduced compared to the single-SNP analysis. They do not report on whether the evidence for locus 1 and locus 3 strengthens in the joint analysis compared to single-SNP analysis, as we observed in the CGASP datasets. They do note that there is no obvious residual association with a third SNP after conditioning on either the pairing of locus 1 (rs16969968) and locus 3 (rs588765), or the pairing of locus 1 (rs55853698) and locus 2 (rs6495308). That result is consistent with the correlation and haplotype structure of these three loci discussed previously.
