Chunk #19 — Results — Detection and Distribution of ZNF804A Immunoreactivity

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Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706.

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Western blots showed that ZNF804A immunoreactivity is present in adult and fetal brain (Figure 4A and eFigure 3 in the Supplement). A single band was identified at approximately 140 kDa, similar to that observed in ZNF804A-transfected cells and bacteria9 and corresponding to the predicted molecular weight of 137 kDa. Signal was abolished by the blocking peptide, and the P-13 mouse antibody produced the same banding pattern (eFigure 4 in the Supplement).